A decision on whether to call up a replacement will be made within the next day. The Springbok group assembled in Johannesburg on Monday to start with preparations for the month-long tour, which kicks off on 11 November against Ireland in Dublin.

“Today is an important day for us as we evaluate all the players regarding their current injury status,” explained Dr Konrad von Hagen, the Springbok team doctor.

“The injury of Jean-Luc was investigated further in Durban and it revealed a fractured ankle. He will see a specialist regarding the management of the injury, which has unfortunately ruled him out of the tour.

“Eben Etzebeth will continue with treatment for his ankle sprain. Our medical team will continuously evaluate him, but at this stage his recovery is satisfactory.

“Last week our goals were achieved regarding the medical assessments, fitness and skills training and this week we are looking forward to continue with our tour preparations.”

The Springboks will fly out to Dublin at the end of the week in two groups, for their Tests against Ireland, France, Italy and Wales.