The Spanish superstar and 22-time Grand Slam champion was knocked out in a straight-sets defeat to Mackenzie Mcdonald.

The 27-year-old American served 14 aces as he sent the top-seeded Nadal crashing out with a 6-4, 6-4 and 7-5 win.

Nadal started battling with a hip injury during the second set. While his pain was visible the 36-year-old soldiered on.

“I tried to keep playing without increasing the damage. But I just wanted to finish the match,” said Nadal.

“Mackenzie was playing at a great level of tennis. A long time I was there, fighting, having my chances, but he was doing well.

“I was not doing that well. I'm tired of talking about my injuries. I lost the match. That's it. I tried till the end.”

Meanwhile, in the women's singles the 7th seeded Coco Gauff knocked Emma Raducanu out with a 6-3 and 7-6 win.

Morgan Piek OFM Sport