The property - 18 Avonwold Road, Saxonwold - is the same house from which Tshepiso Magashule, son of ANC secretary general, was forcefully removed, according to a report by the Mail & Guardian last month.
Park Village Auctions is set to auction the 1 119m2 luxury home at 11:00 on Monday.
The home comprises an entrance foyer, a lounge, a TV room, a dining room, a kitchen, three bedrooms and two bathrooms.
Park Village Auctions adds that the property has a covered patio with access to a garden area and swimming pool located at the front of the dwelling and also features outbuildings
More Gupta-owned properties are reportedly expected to also go under the hammer, reported BusinessLive on Friday.